Objective To compare the clinical effects of preoperative reduction jaundice by percutaneous transhepatic cholangial drainage (PTCD) and endoscopic nasobiliary drainage (ENBD) for choledochal malignant obstructive jaundice. Methods A total of 77 cases with choledochal malignant obstructive jaundice admitted in Eastern Hepatobiliary Surgery Hospital from Aug. 2016 to Mar. 2018 were retrospectively analyzed. Patients were divided into two groups, 41 cases received PTCD (PTCD group), and 36 cases received ENBD (ENBD group). The operation costs, clinical effects and postoperative complication incidences were compared between two groups. Results There was no significant difference on general information before treatment (P>0.05). The operation costs in PTCD group and ERCP group were (2 943.6±412.5) yuan and (5 792.2±312.2) yuan respectively, and the difference was statistically significant (t=34.404, P<0.05). The amount of bile drained in PTCD group was more than ENBD group (F=58.613, P<0.05). The levels of serum bilirubin, gamma glutamate transpeptidase and glutamate transaminase in PTCD group were all lower than those in ENBD group (F=12.8, P<0.05; F=5.214, P<0.05; F=5.724, P<0.05). Conclusion For patients with choledochal malignant obstructive jaundice, both PTCD and ENBD can obtain good clinical effect of the preoperative jaundice reduction. And PTCD approach can obtain better result and lower operation cost.

percutaneous transhepatic cholangial drainage, endoscopic nasobiliary drainage, malignant obstructive jaundice,