肝胆胰外科杂志 ›› 2019, Vol. 31 ›› Issue (9): 540-544.doi: 10.11952/j.issn.1007-1954.2019.09.007

• 论著 临床研究 • 上一篇    下一篇

射频消融治疗肝血管瘤100例分析

李廷军 1 ,符亚辉 2 ,吴辉 1 ,郑文建 1 ,高伟 1 ,逯清忠 1 ,张东 1   

  1. (新疆乌鲁木齐新疆军区总医院,新疆 乌鲁木齐 83000,1.肝胆外科;2.肿瘤科)
  • 收稿日期:2018-12-26 出版日期:2019-09-07 发布日期:2019-10-14
  • 作者简介:李廷军(1977-),男,河南濮阳人,主治医师,博士。

Radiofrequency ablation for treating hepatic hemangioma: a retrospective analysis of 100 cases

LI Ting-jun 1 , FU Ya-hui 2 , WU Hui 1 , ZHENG Wen-jian 1 , GAO Wei 1 , LU Qing-zhong 1 , ZHANG Dong 1 .   

  1. 1 Department of Hepatobiliary Surgery 2 Department of Oncology, General Hospital of Xinjiang Military Area Command,Urumqi, Xinjiang, 830000, China
  • Received:2018-12-26 Online:2019-09-07 Published:2019-10-14

摘要:

目的 总结射频消融(radiofrequency ablation,RFA)治疗肝血管瘤的临床经验。方法 回顾性分析新疆军区总医院2013年3月至2017年10月采用RFA治疗的100例共101个肝血管瘤结节的病例资料。对RFA治疗前后最大瘤体直径的变化及治疗后出血、血尿、肾功能损害等并发症情况进行统计分析。结果 101个结节中88个结节经RFA后完全毁损,完全毁损率87.1%;其中直径≤4 cm的血管瘤完全消融率92.1%(35/38),直径>4 cm的血管瘤完全消融率84.1%(53/63)。RFA术后1个月所有瘤体平均直径由从术前的(4.2±1.8) (2~11)cm降为术后的(2.1±1.8) (0~6)cm,差异有统计学意义(P=0.03)。一个血管瘤治疗前直径为11 cm,经RFA治疗后缩小54.5%。术后52%(52/100)的患者出现发热,体温37.5~38.5 ℃,物理降温后体温均可正常。未经抗生素处理,术后3~5 d后均未出现发热,未出现术后严重并发症。射频消融治疗肝血管瘤安全、有效,特别是对于瘤体较小的血管瘤效果更明显。需要注意的是应该根据血管瘤的大小、局部毗邻关系及分布特点采用个体化的射频治疗方式。

关键词: 肝血管瘤, 射频消融

Abstract:

objective To investigate the clinical effect and experience of radiofrequency ablation (RFA) on the treatment of hepatic hemangioma. Methods Clinical data of 100 patients with a total of 101 hepatic hemangiomas treated by RFA from Mar. 2013 to Oct. 2017 in General Hospital of Xinjiang Military Area Command were retrospectively analyzed. Pre-and-post-RFA maximum diameter of tumor and postoperative complications of hemorrhage, hematuria, renal dysfunction and others were statistically analyzed. Results Among 101 hepatic hemangiomas, 88 were completely ablated, with a complete ablation rate of 87.1%; hemangiomas with diameter ≤4 cm had a complete ablation rate of 92.1% (35/38) and with diameter >4 cm had a complete ablation rate of 84.1% (53/63). One month after RFA, average diameter of all hemangiomas was decreased from (4.2±1.8) (2~11) cm to (2.1±1.8) (0~6) cm, with statistically significant difference (P=0.03). Maximum diameter of a hemangioma with diameter of 11 cm was reduced by 54.4% after RFA. And 52% patients (52/100) had fever, with the highest body temperature of 37.5~38.5 ℃, which became normal after physical cooling without antibiotic treatment. Three to five days later, no fever occurred; no serious complications occurred. All patients had no serious postoperative complication. Conclusion RFA is a safe and effective way for treating hepatic hemangiomas, especially with more obvious effectiveness for small-size hepatic hemangiomas. But the individualized RFA should be adopted according to hepatic hemangiomas’ size, local relationship and distribution characteristics.

Key words: hepatic hemangioma, radiofrequency ablation

中图分类号: 

  • R735.7
[1] 曾庆彬, 徐蓉, 龙奎, 董文志, 孙翊程.
吲哚菁绿荧光导航腹腔镜肝血管瘤剥除术的疗效分析
[J]. 肝胆胰外科杂志, 2023, 35(9): 549-553.
[2] 卢伟业 , 陈志辉 , 颜建飞 , 宋晶晶 , 陈方红.
超声引导下射频消融治疗3~5 cm肝细胞癌的临床效果对照研究
[J]. 肝胆胰外科杂志, 2023, 35(8): 454-458.
[3] 邵天胤, 余俊, 周洪浩, 李园秋, 申雪晗, 董汉华, 张志伟, 陈孝平.
腹腔镜肝切除术与腹腔镜微波消融术治疗肝血管瘤的有效性和安全性研究
[J]. 肝胆胰外科杂志, 2023, 35(11): 660-667.
[4] 崔金涛, 许建生. 钆塞酸二钠增强MRI影像组学对肝血管瘤腹腔镜肝切除术后疗效的预测价值[J]. 肝胆胰外科杂志, 2022, 34(5): 271-278.
[5] 樊啸, 张驰豪, 夏焱. 射频消融与手术切除治疗肿瘤最大径≤5 cm孤立性肝细胞癌的疗效比较[J]. 肝胆胰外科杂志, 2022, 34(4): 198-204.
[6] 伍锦香, 王贵福, 吴青松, 缪辉来. 肝血管瘤合并肝原发性淋巴瘤一例[J]. 肝胆胰外科杂志, 2022, 34(4): 244-246.
[7] 朱江, 黄海军, 庄云峰, 宋思凯, 朱时雨, 梅虎, 张军. CT联合超声引导精准经皮肝穿刺技术在肝VIII段病灶治疗中的应用[J]. 肝胆胰外科杂志, 2022, 34(2): 83-87.
[8] 陈丽, 郑丽云, 方世记, 陈敏江, 应希慧, 吴发宗, 赵中伟, 涂建飞, 纪建松.
不同时间间隔经肝动脉化疗栓塞联合射频消融治疗中晚期肝癌的疗效及安全性
[J]. 肝胆胰外科杂志, 2021, 33(10): 590-.
[9] 陈书德, 林一鹏, 张文智, 卢鹏, 陈志晔. 吲哚菁绿试验对小肝癌治疗策略选择的临床应用分析[J]. 肝胆胰外科杂志, 2020, 32(9): 516-525.
[10] 严康, 刘玮, 秦学敏, 柏根基. 老年复发性小肝癌患者行再切除术与经皮射频消融术的疗效分析[J]. 肝胆胰外科杂志, 2020, 32(5): 286-289.
[11] 邢人伟, 殷平, 聂寒秋, 李文巨, 张阳, 牟永华. 超声引导下射频消融术与腹腔镜肝部分切除术治疗小肝癌的比较分析[J]. 肝胆胰外科杂志, 2020, 32(3): 133-137.
[12] 庄李磊, 雷鑫明, 童秀萍, 王海英, 陆小锋 . 射频消融术与传统手术治疗小肝癌疗效与安全性的Meta分析[J]. 肝胆胰外科杂志, 2020, 32(3): 157-163.
[13] 刘铭, 邢宝才.
术中射频消融在结直肠癌肝转移治疗中的应用
[J]. 肝胆胰外科杂志, 2020, 32(12): 705-714.
[14] 陈德华, 高志强, 马雪松, 申鹏程, 唐哲. 经皮射频消融治疗复发性肝癌的疗效及预后因素分析[J]. 肝胆胰外科杂志, 2019, 31(6): 340-351.
[15] 金克敏, 邢宝才. 结直肠癌肝转移根治性局部治疗手段的比较与选择[J]. 肝胆胰外科杂志, 2019, 31(4): 193-.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!
Copyright © 2017 肝胆胰外科杂志 All Rights Reserved.
电话/传真:0577-86699363 E-mail: gdywkzz@vip.126.com
地址:浙江省温州市茶山高教园区温州医科大学图书馆A411室 邮编:325035
本系统由北京玛格泰克科技发展有限公司设计开发 技术支持:support@magtech.com.cn